Chemical name: 2,4-Oxazolidinedione, 3-(3,5-dichlorophenyl)-5-ethenyl-5-methyl- Final regulatory action has been taken for the category: Pesticide Final regulatory action: The chemical is Banned Use or uses prohibited by the final regulatory action: The approved use was restricted from vegetables, ornamental plants out of doors and in greenhouses, in fruits and some berries and grasslands to only oil plants and ornamental plants in nurseries. After the product was withdrawn it is now prohibited to import, sell or use vinclozolin as a pesticide. Pesticide use or uses that remain allowed: None. The final regulatory action was based on a risk or hazard evaluation: Yes Summary of the final regulatory action: The approved use was restricted from vegetables, ornamental plants out of doors and in greenhouses, in fruits and some berries and grasslands to only oil plants and ornamental plants in nurseries. After the product was withdrawn by the norwegian importer, it is now prohibited to import, sell or use vinclozolin as a pesticide. The reasons for the final regulatory action were relevant to: Human health Summary of known hazards and risks to human health: Vinclozolin is a reproductive toxin. It causes infertility in rats due to feminization of the outer genital organs. Studies have confirmed the anti-androgenic properties of vinclozolin, which are likely to be associated with binding to the androgen receptor. In long-term studies there have also been seen a number of effects such as hepatoxicity, Leydig-cell hyperplasia (and progression to tumors), atrophy of accessory sex glands, atrophic uteri and lipidosis of the adrenal. Expected effect of the final regulatory action in relation to human health: Reduction of risk to human health. Date of entry into force of the final regulatory action: 01/01/1999 |